Optimization question about Clones and Markers

[NightVisions]

If I want to de-tune an instrument then play a note and then de-tune again that same instrument and play a note. Is it easier for computers to load a marker changing the instruments tuning or easier for computers to load 2 clones with different de-tune values.

I would assume it's easier for computers to process clones, but I'm not certain.

[les-toilettes-skibidi]

I'm pretty sure clones are heavier than detune, from what I've seen trying to run sequences on my phone but I maybe not correct